Use of Magnesium Sulphate in Persistent Pulmonary Hypertension of Newborn

The role of magnesium sulphate in the treatment of persistent pulmonary hypertension of the newborn.

Treatment of severe persistent pulmonary hypertension of the newborn with magnesium sulphate.

Eight of nine newborn infants with severe persistent pulmonary hypertension of the newborn (PPHN), and a predicted mortality of 100%, and one infant with a predicted mortality greater than 94% based on alveolar-arterial oxygen tension difference [A-a)DO2) were treated with magnesium sulphate (MgSO4) as a life saving therapy after they failed to improve with conventional treatment. Magnesium at ...

Treatment of seyere persistent pulmonary hypertension of the newborn with magnesium sulphate

Eight of nine newborn infants with severe persistent pulmonary hypertension of the newborn (PPHN), and a predicted mortality of 100%, and one infant with a predicted mortality >94% based on alveolar-arterial oxygen tension difference ((A-a)Do2) were treated with magnesium sulphate (MgSO4) as a life saving therapy after they failed to improve with conventional treatment. Magnesium at high serum ...

Magnesium sulphate as an alternative and safe treatment for severe persistent pulmonary hypertension of the newborn.

Eleven newborns admitted consecutively to the neonatal unit with respiratory failure and severe persistent pulmonary hypertension (PPHN) were included in a clinical trial to assess the efficacy of magnesium sulphate (MgSO4) in the treatment of PPHN. A loading dose of 200 mg/kg MgSO4 was given over 20 minutes, followed by a continuous infusion of 20-150 mg/kg/hour to obtain a magnesium blood con...

Prevalence of Persistent Pulmonary Hypertension of the Newborn and Associated Factors in Term Neonates Born in Southeast of Iran, 2020

 Background and purpose: Infants with persistent pulmonary hypertension (PPHN) are readmitted to hospital three times more than other infants or die after discharge. The disease imposes a high cost on families and health systems. In this study, for the first time, the prevalence of PPHN and associated factors were investigated in mature neonates born in southeast of Iran. Materials and methods...